Search results for "Plateau pressure"

showing 4 items of 4 documents

Do ventilatory parameters influence outcome in patients with severe acute respiratory infection? Secondary analysis of an international, multicentre1…

2021

Purpose: To investigate the possible association between ventilatory settings on the first day of invasive mechanical ventilation (IMV) and mortality in patients admitted to the intensive care unit (ICU) with severe acute respiratory infection (SARI). Materials and methods: In this pre-planned sub-study of a prospective, multicentre observational study, 441 patients with SARI who received controlled IMV during the ICU stay were included in the analysis. Results: ICU and hospital mortality rates were 23.1 and 28.1%, respectively. In multivariable analysis, tidal volume and respiratory rate on the first day of IMV were not associated with an increased risk of death; however, higher driving pr…

ARDSSoins intensifs réanimationmedicine.medical_treatmentAirway pressuresPEEP positive end-expiratory pressureCritical Care and Intensive Care Medicinelaw.inventionHypoxemiaCohort StudiesPositive-Pressure RespirationMechanical ventilationSARI severe acute respiratory infectionlawHospital MortalityProspective StudiesIQR interquartile rangesProspective cohort studyRCT randomized controlled trialTidal volumeSOFA Sequential Organ Failure AssessmentSAPS Simplified Acute Physiology ScoreIntensive care unitVCV volume-controlled ventilationHIV human immunodeficiency virusIntensive Care UnitsIC GLOSSARI Intensive Care Global Study on Severe Acute Respiratory Infectionmedicine.symptomCohort studyLOS length of staymedicine.medical_specialtyVt tidal volumeCOPD Chronic obstructive pulmonary diseaseNYHA New York Heart Association.PCV pressure-controlled ventilationArticleInternal medicineICU Intensive Care UnitSIMV Synchronized intermittent mandatory ventilationmedicineTidal VolumeHumansDP driving pressurePEEPARDS acute respiratory distress syndromeMechanical ventilationbusiness.industryOdds ratioPneumoniaPlateau pressuremedicine.diseaseRespiration ArtificialVILI ventilator induced lung injuryCI confidence intervalOR odds ratioIMV invasive mechanical ventilationCPAP continuous positive airway pressureARDSbusinessSD standard deviationECMO extracorporeal membrane oxygenationPBW predicted body weightPplat plateau pressure
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Corporeal Compression at the Onset of Septic shock (COCOONs): a compression method to reduce fluid balance of septic shock patients

2019

AbstractFluid overload in septic intensive care unit (ICU) patients is common and strongly associated with poor outcome. There is currently no treatment for capillary leak, which is mainly responsible for high positive fluid balance (FB) in sepsis. We hypothesized that increasing interstitial pressure with extensive corporeal compression would reduce FB. The objective of this study was to evaluate the feasibility, efficacy, and safety of a compression treatment during sepsis. This pilot, two-center, single-arm trial enrolled critically ill, non-surgical, septic patients receiving mechanical ventilation. The therapeutic intervention was the early application of compression bandages on more t…

Male0301 basic medicineCritical Caremedicine.medical_treatmentlcsh:MedicinePilot ProjectsTherapeuticsArticlePhase II trialslaw.inventionSepsis03 medical and health sciencesPlateau pressure0302 clinical medicinelawCompression BandagesmedicineClinical endpointHumansProspective StudiesProspective cohort studylcsh:ScienceAgedMechanical ventilationMultidisciplinarybusiness.industrySeptic shocklcsh:RMiddle AgedWater-Electrolyte Balancemedicine.diseaseRespiration ArtificialShock SepticIntensive care unit030104 developmental biologyAnesthesiaShock (circulatory)Femalelcsh:Qmedicine.symptombusiness030217 neurology & neurosurgeryScientific Reports
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Structural heteropolysaccharides as air-tight sealants of the human pleura

2018

Pulmonary "air leaks," typically the result of pleural injury caused by lung surgery or chest trauma, result in the accumulation of air in the pleural space (pneumothorax). Air leaks are a major source of morbidity and prolonged hospitalization after pulmonary surgery. Previous work has demonstrated structural heteropolysaccharide (pectin) binding to the mouse pleural glycocalyx. The similar lectin-binding characteristics and ultrastructural features of the human and mouse pleural glycocalyx suggested the potential application of these polymers in humans. To investigate the utility of pectin-based polymers, we developed a simulacrum using freshly obtained human pleura. Pressure-decay leak t…

Pathologymedicine.medical_specialtyMaterials scienceLungfood.ingredientPectinSealantPerforation (oil well)Biomedical Engineering02 engineering and technologyAdhesion010402 general chemistry021001 nanoscience & nanotechnologymedicine.disease01 natural sciences0104 chemical sciencesBiomaterialsGlycocalyxPlateau pressuremedicine.anatomical_structurefoodPneumothoraxmedicine0210 nano-technologyJournal of Biomedical Materials Research Part B: Applied Biomaterials
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The EasyTube during general anesthesia for minor surgery

2017

BACKGROUND The EasyTube (EzT) is a supraglottic airway device that is used for emergency airway situations. Ventilation during general anesthesia should also be feasible, but literature on the EzT is scarce. We evaluated the EzT in comparison with the endotracheal tube (ETT) in its use during general anesthesia in a comparative study. METHODS A total of 400 patients with American Society of Anesthesiologists (ASA) physical status I to II scheduled for minor surgery in 4 centers were randomized for ventilation via the ETT or EzT. RESULTS In all patients, the EzT and the ETT could be inserted within 3 attempts. In all EzT patients, the inspiratory and expiratory minute volumes (6.64 ± 0.71 an…

business.industry030208 emergency & critical care medicineGeneral MedicineOxygenationlaw.invention03 medical and health sciencesPlateau pressure0302 clinical medicineMinor surgeryRandomized controlled trial030202 anesthesiologylawAnesthesiaCuffSore throatmedicineBreathingmedicine.symptombusinessAirwayMedicine
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